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Amyloid-β Receptors: The Good, the Bad, and the Prion Protein

Several different receptor proteins have been identified that bind monomeric, oligomeric, or fibrillar forms of amyloid-β (Aβ). “Good” receptors internalize Aβ or promote its transcytosis out of the brain, whereas “bad” receptors bind oligomeric forms of Aβ that are largely responsible for the synap...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Jarosz-Griffiths, Heledd H., Noble, Elizabeth, Rushworth, Jo V., Hooper, Nigel M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751366/
https://ncbi.nlm.nih.gov/pubmed/26719327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R115.702704
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