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Lipid rafts: linking prion protein to zinc transport and amyloid-β toxicity in Alzheimer's disease

Dysregulation of neuronal zinc homeostasis plays a major role in many processes related to brain aging and neurodegenerative diseases, including Alzheimer's disease (AD). Yet, despite the critical role of zinc in neuronal function, the cellular mechanisms underpinning its homeostatic control ar...

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Detalhes bibliográficos
Main Authors: Watt, Nicole T., Griffiths, Heledd H., Hooper, Nigel M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4206978/
https://ncbi.nlm.nih.gov/pubmed/25364748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2014.00041
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