TspanC8 Tetraspanins and A Disintegrin and Metalloprotease 10 (ADAM10) Interact via Their Extracellular Regions: EVIDENCE FOR DISTINCT BINDING MECHANISMS FOR DIFFERENT TspanC8 PROTEINS

A disintegrin and metalloprotease 10 (ADAM10) is a ubiquitously expressed transmembrane metalloprotease that cleaves the extracellular regions from its transmembrane substrates. ADAM10 is essential for embryonic development and is implicated in cancer, Alzheimer, and inflammatory diseases. The tetra...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Noy, Peter J., Yang, Jing, Reyat, Jasmeet S., Matthews, Alexandra L., Charlton, Alice E., Furmston, Joanna, Rogers, David A., Rainger, G. Ed, Tomlinson, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751363/
https://ncbi.nlm.nih.gov/pubmed/26668317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.703058
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