Influence of ejection fraction on outcomes and efficacy of spironolactone in patients with heart failure with preserved ejection fraction

AIMS: While mineralocorticoid receptor antagonists (MRAs) have been shown to benefit patients with reduced left ventricular ejection fraction (LVEF), spironolactone did not reduce the primary endpoint of cardiovascular death, heart failure hospitalization, or aborted cardiac arrest in patients with...

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Détails bibliographiques
Publié dans:Eur Heart J
Auteurs principaux: Solomon, Scott D., Claggett, Brian, Lewis, Eldrin F., Desai, Akshay, Anand, Inder, Sweitzer, Nancy K., O'Meara, Eileen, Shah, Sanjiv J., McKinlay, Sonja, Fleg, Jerome L., Sopko, George, Pitt, Bertram, Pfeffer, Marc A.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2016
Sujets:
Clinical Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751235/
https://ncbi.nlm.nih.gov/pubmed/26374849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehv464
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