Influence of ejection fraction on outcomes and efficacy of spironolactone in patients with heart failure with preserved ejection fraction

AIMS: While mineralocorticoid receptor antagonists (MRAs) have been shown to benefit patients with reduced left ventricular ejection fraction (LVEF), spironolactone did not reduce the primary endpoint of cardiovascular death, heart failure hospitalization, or aborted cardiac arrest in patients with...

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Udgivet i:Eur Heart J
Main Authors: Solomon, Scott D., Claggett, Brian, Lewis, Eldrin F., Desai, Akshay, Anand, Inder, Sweitzer, Nancy K., O'Meara, Eileen, Shah, Sanjiv J., McKinlay, Sonja, Fleg, Jerome L., Sopko, George, Pitt, Bertram, Pfeffer, Marc A.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
Clinical Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751235/
https://ncbi.nlm.nih.gov/pubmed/26374849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehv464
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