Botulinum and Tetanus Neurotoxin-Induced Blockade of Synaptic Transmission in Networked Cultures of Human and Rodent Neurons

Clinical manifestations of tetanus and botulism result from an intricate series of interactions between clostridial neurotoxins (CNTs) and nerve terminal proteins that ultimately cause proteolytic cleavage of SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) proteins and...

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Bibliografische gegevens
Gepubliceerd in:Toxicol Sci
Hoofdauteurs: Beske, Phillip H., Bradford, Aaron B., Grynovicki, Justin O., Glotfelty, Elliot J., Hoffman, Katie M., Hubbard, Kyle S., Tuznik, Kaylie M., McNutt, Patrick M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2016
Onderwerpen:
Networked Cultures to Study Neurotoxin Actions on Synaptic Transmission
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751230/
https://ncbi.nlm.nih.gov/pubmed/26615023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv254
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