Effect of the 5-lipoxygenase inhibitor ZD2138 on allergen-induced early and late asthmatic responses.

BACKGROUND--Leukotrienes are lipid mediators generated from arachidonic acid by the 5-lipoxygenase pathway which may play an important part in the pathophysiology of asthma. Previous studies have demonstrated attenuation of the allergen-induced early and late asthmatic responses by leukotriene recep...

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Publicat a:	Thorax
Autors principals:	Nasser, S. M., Bell, G. S., Hawksworth, R. J., Spruce, K. E., MacMillan, R., Williams, A. J., Lee, T. H., Arm, J. P.
Format:	Artigo
Idioma:	Inglês
Publicat:	BMJ Publishing Group 1994
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC475117/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8091317/ https://ncbi.nlm.nih.govhttps://doi.org/10.1136/thx.49.8.743
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