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Effect of the 5-lipoxygenase inhibitor ZD2138 on allergen-induced early and late asthmatic responses.

BACKGROUND--Leukotrienes are lipid mediators generated from arachidonic acid by the 5-lipoxygenase pathway which may play an important part in the pathophysiology of asthma. Previous studies have demonstrated attenuation of the allergen-induced early and late asthmatic responses by leukotriene recep...

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Autori principali: Nasser, S. M., Bell, G. S., Hawksworth, R. J., Spruce, K. E., MacMillan, R., Williams, A. J., Lee, T. H., Arm, J. P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1994
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC475117/
https://ncbi.nlm.nih.gov/pubmed/8091317
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