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T1ρ Imaging in Premanifest Huntington Disease Reveals Changes Associated with Disease Progression

BACKGROUND: Imaging biomarkers sensitive to Huntington’s disease (HD) during the premanifest phase preceding motor diagnosis may accelerate identification and evaluation of potential therapies. For this purpose, quantitative MRI sensitive to tissue microstructure and metabolism may hold great potent...

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Detalhes bibliográficos
Publicado no:Mov Disord
Main Authors: Wassef, Shafik N., Wemmie, John, Johnson, Casey P., Johnson, Hans, Paulsen, Jane S., Long, Jeffrey D., Magnotta, Vincent A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751081/
https://ncbi.nlm.nih.gov/pubmed/25820773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.26203
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