Metabolic network as a progression biomarker of premanifest Huntington’s disease

Background. The evaluation of effective disease-modifying therapies for neurodegenerative disorders relies on objective and accurate measures of progression in at-risk individuals. Here we used a computational approach to identify a functional brain network associated with the progression of preclin...

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Autori principali: Tang, Chris C., Feigin, Andrew, Ma, Yilong, Habeck, Christian, Paulsen, Jane S., Leenders, Klaus L., Teune, Laura K., van Oostrom, Joost C.H., Guttman, Mark, Dhawan, Vijay, Eidelberg, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2013
Soggetti:
Clinical Medicine
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754266/
https://ncbi.nlm.nih.gov/pubmed/23985564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI69411
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