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Angiotensin II Type 2 Receptor Decreases Transforming Growth Factor-β Type II Receptor Expression and Function in Human Renal Proximal Tubule Cells
Transforming growth factor-β (TGF-β), via its receptors, induces epithelial-mesenchymal transition (EMT) and plays an important role in the development of renal tubulointersitial fibrosis. Angiotensin II type 2 receptor (AT(2)R), which mediates beneficial renal physiological functions, has received...
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| Опубликовано в: : | PLoS One |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4750982/ https://ncbi.nlm.nih.gov/pubmed/26867007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148696 |
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