Analysis of the Structure and Function of FOX-4 Cephamycinase

Class C β-lactamases poorly hydrolyze cephamycins (e.g., cefoxitin, cefotetan, and moxalactam). In the past 2 decades, a new family of plasmid-based AmpC β-lactamases conferring resistance to cefoxitin, the FOX family, has grown to include nine unique members descended from the Aeromonas caviae chro...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Lefurgy, S. T., Malashkevich, V. N., Aguilan, J. T., Nieves, E., Mundorff, E. C., Biju, B., Noel, M. A., Toro, R., Baiwir, D., Papp-Wallace, K. M., Almo, S. C., Frere, J.-M., Bou, G., Bonomo, R. A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
Témata:
Mechanisms of Resistance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750714/
https://ncbi.nlm.nih.gov/pubmed/26525784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01887-15
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