Cytosolic phospholipase A(2)α regulates G(1) progression through modulating FOXO1 activity

Group IVA phospholipase A(2) [cytosolic phospholipase A(2)α (cPLA(2)α)] is a key mediator of inflammation and tumorigenesis. In this study, by using a combination of chemical inhibition and genetic approaches in zebrafish and murine cells, we identify a mechanism by which cPLA(2)α promotes cell prol...

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Dettagli Bibliografici
Pubblicato in:FASEB J
Autori principali: Naini, Said Movahedi, Choukroun, Gabriel J., Ryan, James R., Hentschel, Dirk M., Shah, Jagesh V., Bonventre, Joseph V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Federation of American Societies for Experimental Biology 2016
Soggetti:
Research Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750418/
https://ncbi.nlm.nih.gov/pubmed/26644349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-278416
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