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Monomeric Aβ(1–40) and Aβ(1–42) Peptides in Solution Adopt Very Similar Ramachandran Map Distributions That Closely Resemble Random Coil
[Image: see text] The pathogenesis of Alzheimer’s disease is characterized by the aggregation and fibrillation of amyloid peptides Aβ(1–40) and Aβ(1–42) into amyloid plaques. Despite strong potential therapeutic interest, the structural pathways associated with the conversion of monomeric Aβ peptide...
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| Publicado no: | Biochemistry |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American
Chemical Society
2016
|
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4750080/ https://ncbi.nlm.nih.gov/pubmed/26780756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b01259 |
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