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Mammalian cells lacking either the cotranslational or posttranslocational oligosaccharyltransferase complex display substrate-dependent defects in asparagine linked glycosylation

Asparagine linked glycosylation of proteins is an essential protein modification reaction in most eukaryotic organisms. Metazoan organisms express two oligosaccharyltransferase complexes that are composed of a catalytic subunit (STT3A or STT3B) assembled with a shared set of accessory subunits and o...

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Foilsithe in:Sci Rep
Main Authors: Cherepanova, Natalia A., Gilmore, Reid
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750078/
https://ncbi.nlm.nih.gov/pubmed/26864433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20946
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