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Cotranslational and Posttranslational N-Glycosylation of Polypeptides by Distinct Mammalian OST Isoforms

Asparagine-linked glycosylation of polypeptides in the lumen of the endoplasmic reticulum is catalyzed by the hetero-oligomeric oligosaccharyltransferase (OST). OST isoforms with different catalytic subunits (STT3A versus STT3B) and distinct enzymatic properties are coexpressed in mammalian cells. U...

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Détails bibliographiques
Auteurs principaux: Ruiz-Canada, Catalina, Kelleher, Daniel J., Gilmore, Reid
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859625/
https://ncbi.nlm.nih.gov/pubmed/19167329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.11.047
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