5-hydroxymethylcytosine loss is associated with poor prognosis for patients with WHO grade II diffuse astrocytomas

Currently, the reliable prognostic biomarkers for WHO grade II diffuse astrocytomas (DA) are still limited. We investigated the relations between the level of 5-Hydroxymethylcytosine (5hmC), an oxidated production of 5-methylcytosine (5mC) by the ten eleven translocated (TET) enzymes, and clinicopat...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Feng, Liu, Yifan, Zhang, Zhiwen, Li, Jie, Wan, Yi, Zhang, Liying, Wang, Yangmei, Li, Xia, Xu, Yuqiao, Fu, Xin, Zhang, Xiumin, Zhang, Ming, Zhang, Zhekai, Zhang, Jing, Yan, Qingguo, Ye, Jing, Wang, Zhe, Chen, Charlie Degui, Lin, Wei, Li, Qing
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749994/
https://ncbi.nlm.nih.gov/pubmed/26864347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20882
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