5-hydroxymethylcytosine loss is associated with poor prognosis for patients with WHO grade II diffuse astrocytomas

Currently, the reliable prognostic biomarkers for WHO grade II diffuse astrocytomas (DA) are still limited. We investigated the relations between the level of 5-Hydroxymethylcytosine (5hmC), an oxidated production of 5-methylcytosine (5mC) by the ten eleven translocated (TET) enzymes, and clinicopat...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Zhang, Feng, Liu, Yifan, Zhang, Zhiwen, Li, Jie, Wan, Yi, Zhang, Liying, Wang, Yangmei, Li, Xia, Xu, Yuqiao, Fu, Xin, Zhang, Xiumin, Zhang, Ming, Zhang, Zhekai, Zhang, Jing, Yan, Qingguo, Ye, Jing, Wang, Zhe, Chen, Charlie Degui, Lin, Wei, Li, Qing
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749994/
https://ncbi.nlm.nih.gov/pubmed/26864347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20882
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