Targeted deletion of miR-132/-212 impairs memory and alters the hippocampal transcriptome

miR-132 and miR-212 are structurally related microRNAs that have been found to exert powerful modulatory effects within the central nervous system (CNS). Notably, these microRNAs are tandomly processed from the same noncoding transcript, and share a common seed sequence: thus it has been difficult t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Learn Mem
Prif Awduron: Hansen, Katelin F., Sakamoto, Kensuke, Aten, Sydney, Price, Kaiden H., Loeser, Jacob, Hesse, Andrea M., Page, Chloe E., Pelz, Carl, Arthur, J. Simon C., Impey, Soren, Obrietan, Karl
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2016
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749831/
https://ncbi.nlm.nih.gov/pubmed/26773099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.039578.115
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