Targeted deletion of miR-132/-212 impairs memory and alters the hippocampal transcriptome

miR-132 and miR-212 are structurally related microRNAs that have been found to exert powerful modulatory effects within the central nervous system (CNS). Notably, these microRNAs are tandomly processed from the same noncoding transcript, and share a common seed sequence: thus it has been difficult t...

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Publicado en:Learn Mem
Main Authors: Hansen, Katelin F., Sakamoto, Kensuke, Aten, Sydney, Price, Kaiden H., Loeser, Jacob, Hesse, Andrea M., Page, Chloe E., Pelz, Carl, Arthur, J. Simon C., Impey, Soren, Obrietan, Karl
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2016
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749831/
https://ncbi.nlm.nih.gov/pubmed/26773099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.039578.115
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