Targeted deletion of miR-132/-212 impairs memory and alters the hippocampal transcriptome

miR-132 and miR-212 are structurally related microRNAs that have been found to exert powerful modulatory effects within the central nervous system (CNS). Notably, these microRNAs are tandomly processed from the same noncoding transcript, and share a common seed sequence: thus it has been difficult t...

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Vydáno v:Learn Mem
Hlavní autoři: Hansen, Katelin F., Sakamoto, Kensuke, Aten, Sydney, Price, Kaiden H., Loeser, Jacob, Hesse, Andrea M., Page, Chloe E., Pelz, Carl, Arthur, J. Simon C., Impey, Soren, Obrietan, Karl
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2016
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749831/
https://ncbi.nlm.nih.gov/pubmed/26773099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.039578.115
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