Upregulation and Mitochondrial Sequestration of Hemoglobin Occur in Circulating Leukocytes during Critical Illness, Conferring a Cytoprotective Phenotype

The classical role of hemoglobin in the erythrocytes is to carry oxygen from the lungs to the tissues via the circulation. However, hemoglobin also acts as a redox regulator and as a scavenger of the gaseous mediators nitric oxide (NO) and hydrogen sulfide (H(2)S). Here we show that upregulation of...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Med
Egile Nagusiak: Brunyanszki, Attila, Erdelyi, Katalin, Szczesny, Bartosz, Olah, Gabor, Salomao, Reinaldo, Herndon, David N, Szabo, Csaba
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Feinstein Institute Press 2015
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749489/
https://ncbi.nlm.nih.gov/pubmed/26322851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2015.00187
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