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Upregulation and Mitochondrial Sequestration of Hemoglobin Occur in Circulating Leukocytes during Critical Illness, Conferring a Cytoprotective Phenotype
The classical role of hemoglobin in the erythrocytes is to carry oxygen from the lungs to the tissues via the circulation. However, hemoglobin also acts as a redox regulator and as a scavenger of the gaseous mediators nitric oxide (NO) and hydrogen sulfide (H(2)S). Here we show that upregulation of...
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| Wydane w: | Mol Med |
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| Główni autorzy: | , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
The Feinstein Institute Press
2015
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4749489/ https://ncbi.nlm.nih.gov/pubmed/26322851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2015.00187 |
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