Interleukin-1 augments salt retention in angiotensin II-induced hypertension via nitric oxide-dependent regulation of the NKCC2 sodium co-transporter

Hypertension is among the most prevalent and catastrophic chronic diseases worldwide. While the efficacy of renin angiotensin system (RAS) blockade in lowering blood pressure illustrates that the RAS is broadly activated in human hypertension, the frequent failure of RAS inhibition to prevent or rev...

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Publicat a:Cell Metab
Autors principals: Zhang, Jiandong, Rudemiller, Nathan P., Patel, Mehul B., Karlovich, Norah S., Wu, Min, McDonough, Alicia A., Griffiths, Robert, Sparks, Matthew A., Jeffs, Alexander D., Crowley, Steven D.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749461/
https://ncbi.nlm.nih.gov/pubmed/26712462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2015.11.013
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