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One-pot synthesis of GABA amides via the nucleophilic addition of amines to 3,3-disubstituted cyclopropenes

A one-pot synthesis of various GABA amides has been demostrated, employing the nucleophilic addition of primary and secondary amines across the double bond of cyclopropene-3-carboxamides, followed by ring-opening of the resulting donor-acceptor cyclopropanes and subsequent in situ reduction of enami...

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Bibliografiske detaljer
Udgivet i:Org Biomol Chem
Main Authors: Maslivetc, Vladimir A., Rubina, Marina, Rubin, Michael
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749319/
https://ncbi.nlm.nih.gov/pubmed/26243009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5ob01462j
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