DAF-16 and TCER-1 Facilitate Adaptation to Germline Loss by Restoring Lipid Homeostasis and Repressing Reproductive Physiology in C. elegans

Elimination of the proliferating germline extends lifespan in C. elegans. This phenomenon provides a unique platform to understand how complex metazoans retain metabolic homeostasis when challenged with major physiological perturbations. Here, we demonstrate that two conserved transcription regulato...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Amrit, Francis Raj Gandhi, Steenkiste, Elizabeth Marie, Ratnappan, Ramesh, Chen, Shaw-Wen, McClendon, T. Brooke, Kostka, Dennis, Yanowitz, Judith, Olsen, Carissa Perez, Ghazi, Arjumand
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749232/
https://ncbi.nlm.nih.gov/pubmed/26862916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005788
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