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DNA concentration and length in sputum of patients with cystic fibrosis during inhalation with recombinant human DNase.

BACKGROUND--The clinical benefit of the administration of aerosolised recombinant human DNase (rhDNase) on pulmonary function in patients with cystic fibrosis has already been demonstrated but the biochemical action of rhDNase on DNA in bronchial secretions in vivo has not yet been investigated. MET...

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Detalles Bibliográficos
Main Authors: Brandt, T., Breitenstein, S., von der Hardt, H., Tümmler, B.
Formato: Artigo
Idioma:Inglês
Publicado: 1995
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC474911/
https://ncbi.nlm.nih.gov/pubmed/7570441
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