Pharmacokinetic/Toxicity Properties of the New Anti-Staphylococcal Lead Compound SK-03-92

Because of the potential of a new anti-staphylococcal lead compound SK-03-92 as a topical antibiotic, a patch, or an orally active drug, we sought to determine its safety profile and oral bioavailability. SK-03-92 had a high IC(50) (125 μg/mL) in vitro against several mammalian cell lines, and mice...

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Detalhes bibliográficos
Publicado no:Antibiotics (Basel)
Main Authors: Schwan, William R., Kolesar, Jill M., Kabir, M. Shahjahan, Elder, Edmund J., Williams, Jeffrey B., Minerath, Rachel, Cook, James M., Witzigmann, Christopher M., Monte, Aaron, Flaherty, Tricia
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4748848/
https://ncbi.nlm.nih.gov/pubmed/26877886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics4040617
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