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A DEAD-box RNA helicase promotes thermodynamic equilibration of kinetically trapped RNA structures in vivo
RNAs must assemble into specific structures in order to carry out their biological functions, but in vitro RNA folding reactions produce multiple misfolded structures that fail to exchange with functional structures on biological time scales. We used carefully designed self-cleaving mRNAs that assem...
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| Publicado no: | RNA |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4748819/ https://ncbi.nlm.nih.gov/pubmed/26759451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.055178.115 |
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