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A DEAD-box RNA helicase promotes thermodynamic equilibration of kinetically trapped RNA structures in vivo
RNAs must assemble into specific structures in order to carry out their biological functions, but in vitro RNA folding reactions produce multiple misfolded structures that fail to exchange with functional structures on biological time scales. We used carefully designed self-cleaving mRNAs that assem...
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| Publié dans: | RNA |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Cold Spring Harbor Laboratory Press
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4748819/ https://ncbi.nlm.nih.gov/pubmed/26759451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.055178.115 |
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