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A DEAD-box RNA helicase promotes thermodynamic equilibration of kinetically trapped RNA structures in vivo
RNAs must assemble into specific structures in order to carry out their biological functions, but in vitro RNA folding reactions produce multiple misfolded structures that fail to exchange with functional structures on biological time scales. We used carefully designed self-cleaving mRNAs that assem...
Guardat en:
| Publicat a: | RNA |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4748819/ https://ncbi.nlm.nih.gov/pubmed/26759451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.055178.115 |
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