Eradication of large solid tumors in mice with an immunotoxin directed against tumor vasculature.
Antibody-based therapy of solid tumors has met with limited success, chiefly because solid tumors are relatively impermeable to macromolecules. This problem could be circumvented by attacking the readily accessible endothelial cells of the tumor vascular bed. We have developed a model to test this "...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47488/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7692443/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.19.8996 |
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