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Peptides corresponding to a predictive alpha-helical domain of human immunodeficiency virus type 1 gp41 are potent inhibitors of virus infection.

To define the role of the human immunodeficiency virus type 1 (HIV-1) envelope proteins in virus infection, a series of peptides were synthesized based on various regions of the HIV-1 transmembrane protein gp41. One of these peptides, DP-178, corresponding to a region predictive of alpha-helical sec...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Wild, C T, Shugars, D C, Greenwell, T K, McDanal, C B, Matthews, T J
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44898/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7937889/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.21.9770
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