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Effective leveraging of targeted search spaces for improving peptide identification in MS/MS based proteomics

In shotgun proteomics, peptides are typically identified using database searching which involves scoring acquired tandem mass spectra against peptides derived from standard protein sequence databases such as Uniprot, Refseq, or Ensembl. In this strategy, the sensitivity of peptide identification is...

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Detalhes bibliográficos
Publicado no:J Proteome Res
Main Authors: Shanmugam, Avinash K., Nesvizhski, Alexey I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4748730/
https://ncbi.nlm.nih.gov/pubmed/26569054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.5b00504
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