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Comparative pharmacokinetic evaluation and bioequivalence study of three different formulations of Imatinib Mesylate in CML patients

Background: Imatinib is known as the drug of choice for treatment of chronic myeloid leukemia (CML). For adults the recommended daily dosage of 400 mg requires simultaneous intake of up to four capsules or tablets each 100 mg. A new 400 mg film coated tablet developed due to the need to swallow mult...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Hematol Oncol Stem Cell Res
Hauptverfasser: Mohajeri, Ehsan, Kalantari-Khandani, Behjat, Pardakhty, Abbas, Safavi, Moeinadin, Ansari, Mehdi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Tehran University of Medical Sciences, Hematology-Oncology and Stem Cell Transplantation Research Center 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4748686/
https://ncbi.nlm.nih.gov/pubmed/26865926
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