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Synthesis of the 16S,17S-epoxy-Protectin Intermediate in the Biosynthesis of Protectins by Human Macrophages

The n-3 polyunsaturated fatty acids act as substrates during the resolution phase of acute inflammation for the biosynthesis of specialized pro-resolving lipid mediators. One premier example is the C22-dihydroxy-polyunsaturated fatty acid protectin D1 (1). The human 15-lipoxygenase type I, via stere...

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Detalhes bibliográficos
Publicado no:J Nat Prod
Main Authors: Aursnes, Marius, Tungen, Jørn E., Colas, Romain A., Vlasakov, Iliyan, Dalli, Jesmond, Serhan, Charles N., Hansen, Trond V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4748394/
https://ncbi.nlm.nih.gov/pubmed/26580578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jnatprod.5b00574
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