COMT gene locus: new functional variants

Catechol-O-methyltransferase (COMT) metabolizes catecholaminergic neurotransmitters. Numerous studies have linked COMT to pivotal brain functions such as mood, cognition, response to stress, and pain. Both nociception and risk of clinical pain have been associated with COMT genetic variants, and thi...

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Dades bibliogràfiques
Publicat a:Pain
Autors principals: Meloto, Carolina B., Segall, Samantha K., Smith, Shad, Parisien, Marc, Shabalina, Svetlana A., Rizzatti-Barbosa, Célia M., Gauthier, Josée, Tsao, Douglas, Convertino, Marino, Piltonen, Marjo H., Slade, Gary Dmitri, Fillingim, Roger B., Greenspan, Joel D., Ohrbach, Richard, Knott, Charles, Maixner, William, Zaykin, Dmitri, Dokholyan, Nikolay V., Reenilä, Ilkka, Männistö, Pekka T., Diatchenko, Luda
Format: Artigo
Idioma:Inglês
Publicat: Wolters Kluwer 2015
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4748386/
https://ncbi.nlm.nih.gov/pubmed/26207649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000000273
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