Sorting nexin 27 interacts with Fzd7 and mediates Wnt signalling

SNX27 is the only sorting nexin (SNX) that contains a PDZ domain, which interacts with PDZ-binding motif of target proteins to regulate the trafficking of these proteins. We here showed that SNX27 interacts with Frizzled (Fzd) receptors via PDZ domain interaction. Immunofluorescence microscopy revea...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Biosci Rep
Egile Nagusiak: Sun, Lixiang, Hu, Xiuyong, Chen, Wanming, He, Wei, Zhang, Zhiming, Wang, Tuanlao
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Portland Press Ltd. 2016
Gaiak:
Original Papers
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4748333/
https://ncbi.nlm.nih.gov/pubmed/26744382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20150205
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