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Steroidogenesis and early response gene expression in MA-10 Leydig tumor cells following heterologous receptor down-regulation and cellular desensitization

The Leydig tumor cell line, MA-10, expresses the luteinizing hormone receptor, a G protein-coupled receptor that, when activated with luteinizing hormone or chorionic gonadotropin (CG), stimulates cAMP production and subsequent steroidogenesis, notably progesterone. These cells also respond to epide...

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Publicat a:Biochem Biophys Rep
Autors principals: Chen, Tsuey-Ming, Czerwiec, Frank S., Puett, David
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4748167/
https://ncbi.nlm.nih.gov/pubmed/26878066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2016.01.005
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