Endosialin and Associated Protein Expression in Soft Tissue Sarcomas: A Potential Target for Anti-Endosialin Therapeutic Strategies

Endosialin (CD248, TEM-1) is expressed in pericytes, tumor vasculature, tumor fibroblasts, and some tumor cells, including sarcomas, with limited normal tissue expression, and appears to play a key role in tumor-stromal interactions, including angiogenesis. Monoclonal antibodies targeting endosialin...

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Detalhes bibliográficos
Publicado no:Sarcoma
Main Authors: O'Shannessy, Daniel J., Dai, Hongyue, Mitchell, Melissa, Huntsman, Shane, Brantley, Stephen, Fenstermacher, David, Reed, Damon R.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4748105/
https://ncbi.nlm.nih.gov/pubmed/27057137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/5213628
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