Endosialin Expression in Metastatic Melanoma Tumor Microenvironment Vasculature: Potential Therapeutic Implications

Ontuxizumab (MORAb-004) is a humanized recombinant antibody targeting endosialin (TEM-1, CD248). We conducted an analysis of endosialin expression in metastatic melanoma specimens using the anti-endosialin rat anti- MAb 9G5, in order to determine the potential of endosialin as a therapeutic target w...

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Bibliografiske detaljer
Udgivet i:Cancer Microenviron
Main Authors: Kiyohara, Eiji, Donovan, Nicholas, Takeshima, Ling, Huang, Sharon, Wilmott, James S., Scolyer, Richard A., Jones, Peter, Somers, Elizabeth B., O’Shannessy, Daniel J., Hoon, Dave S. B.
Format: Artigo
Sprog:Inglês
Udgivet: Springer Netherlands 2015
Fag:
Brief Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4542822/
https://ncbi.nlm.nih.gov/pubmed/26085332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12307-015-0168-8
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