I kappa B alpha-mediated inhibition of v-Rel DNA binding requires direct interaction with the RXXRXRXXC Rel/kappa B DNA-binding motif.

Liknande verk

• The RxxRxRxxC motif conserved in all Rel/kappa B proteins is essential for the DNA-binding activity and redox regulation of the v-Rel oncoprotein.
  av: Kumar, S, et al.
  Publicerad: (1992)
• Selection of optimal kappa B/Rel DNA-binding motifs: interaction of both subunits of NF-kappa B with DNA is required for transcriptional activation.
  av: Kunsch, C, et al.
  Publicerad: (1992)
• Interaction of the v-rel protein with an NF-kappa B DNA binding site.
  av: Kabrun, N, et al.
  Publicerad: (1991)
• PEST-dependent cytoplasmic retention of v-Rel by I(kappa)B-alpha: evidence that I(kappa)B-alpha regulates cellular localization of c-Rel and v-Rel by distinct mechanisms.
  av: Rottjakob, E M, et al.
  Publicerad: (1996)
• Mutations in the DNA-binding and dimerization domains of v-Rel are responsible for altered kappa B DNA-binding complexes in transformed cells.
  av: Hrdlicková, R, et al.
  Publicerad: (1995)