Mutations in the DNA-binding and dimerization domains of v-Rel are responsible for altered kappa B DNA-binding complexes in transformed cells.

Lignende værker

• Mechanism of Telomerase Activation by v-Rel and Its Contribution to Transformation
  af: Hrdličková, Radmila, et al.
  Udgivet: (2006)
• Interferon Regulatory Factor 4 Contributes to Transformation of v-Rel-Expressing Fibroblasts
  af: Hrdličková, Radmila, et al.
  Udgivet: (2001)
• Mutational Analysis of the v-Rel Dimerization Interface Reveals a Critical Role for v-Rel Homodimers in Transformation
  af: Liss, Andrew S., et al.
  Udgivet: (2002)
• The relocalization of v-Rel from the nucleus to the cytoplasm coincides with induction of expression of Ikba and nfkb1 and stabilization of I kappa B-alpha.
  af: Hrdlicková, R, et al.
  Udgivet: (1995)
• Evolution of the oncogenic potential of v-rel: rel-induced expression of immunoregulatory receptors correlates with tumor development and in vitro transformation.
  af: Nehyba, J, et al.
  Udgivet: (1994)