Aerobic Glycolysis in the Frontal Cortex Correlates with Memory Performance in Wild-Type Mice But Not the APP/PS1 Mouse Model of Cerebral Amyloidosis

Aerobic glycolysis and lactate production in the brain plays a key role in memory, yet the role of this metabolism in the cognitive decline associated with Alzheimer's disease (AD) remains poorly understood. Here we examined the relationship between cerebral lactate levels and memory performanc...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Harris, Richard A., Tindale, Lauren, Lone, Asad, Singh, Olivia, Macauley, Shannon L., Stanley, Molly, Holtzman, David M., Bartha, Robert, Cumming, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2016
Assuntos:
Brief Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4748073/
https://ncbi.nlm.nih.gov/pubmed/26865611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3131-15.2016
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