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Upregulation of basolateral small conductance potassium channels (KCNQ1/KCNE3) in ulcerative colitis

BACKGROUND: Basolateral K(+) channels hyperpolarize colonocytes to ensure Na(+) (and thus water) absorption. Small conductance basolateral (KCNQ1/KCNE3) K(+) channels have never been evaluated in human colon. We therefore evaluated KCNQ1/KCNE3 channels in distal colonic crypts obtained from normal a...

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Publicat a:Biochem Biophys Res Commun
Autors principals: Al-Hazza, Adel, Linley, John, Aziz, Qadeer, Hunter, Malcolm, Sandle, Geoffrey
Format: Artigo
Idioma:Inglês
Publicat: Academic Press 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4748010/
https://ncbi.nlm.nih.gov/pubmed/26718405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2015.12.086
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