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Synthetic gene network restoring endogenous pituitary–thyroid feedback control in experimental Graves’ disease
Graves’ disease is an autoimmune disorder that causes hyperthyroidism because of autoantibodies that bind to the thyroid-stimulating hormone receptor (TSHR) on the thyroid gland, triggering thyroid hormone release. The physiological control of thyroid hormone homeostasis by the feedback loops involv...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4747754/ https://ncbi.nlm.nih.gov/pubmed/26787873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1514383113 |
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