T-cell–intrinsic Tif1α/Trim24 regulates IL-1R expression on T(H)2 cells and T(H)2 cell-mediated airway allergy

There is a paucity of new therapeutic targets to control allergic reactions and forestall the rising trend of allergic diseases. Although a variety of immune cells contribute to allergy, cytokine-secreting αβ(+)CD4(+) T-helper 2 (T(H)2) cells orchestrate the type-2–driven immune response in a large...

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Gardado en:
Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Perez-Lloret, Jimena, Okoye, Isobel S., Guidi, Riccardo, Kannan, Yashaswini, Coomes, Stephanie M., Czieso, Stephanie, Mengus, Gabrielle, Davidson, Irwin, Wilson, Mark S.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2016
Assuntos:
PNAS Plus
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747735/
https://ncbi.nlm.nih.gov/pubmed/26787865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1522287113
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