Transcriptomics identified a critical role for Th2 cell-intrinsic miR-155 in mediating allergy and antihelminth immunity

Allergic diseases, orchestrated by hyperactive CD4(+) Th2 cells, are some of the most common global chronic diseases. Therapeutic intervention relies upon broad-scale corticosteroids with indiscriminate impact. To identify targets in pathogenic Th2 cells, we took a comprehensive approach to identify...

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Detalhes bibliográficos
Main Authors: Okoye, Isobel S., Czieso, Stephanie, Ktistaki, Eleni, Roderick, Kathleen, Coomes, Stephanie M., Pelly, Victoria S., Kannan, Yashaswini, Perez-Lloret, Jimena, Zhao, Jimmy L., Baltimore, David, Langhorne, Jean, Wilson, Mark S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121777/
https://ncbi.nlm.nih.gov/pubmed/25024218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1406322111
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