Optimization of a Human Bacille Calmette-Guérin Challenge Model: A Tool to Evaluate Antimycobacterial Immunity

Background. There is an urgent need for an improved tuberculosis vaccine. The lack of a validated correlate of protection slows progress in achieving this goal. A human mycobacterial challenge model, using bacille Calmette-Guérin (BCG) as a surrogate for a Mycobacterium tuberculosis challenge, would...

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Publicado en:J Infect Dis
Autores principales: Minhinnick, Alice, Harris, Stephanie, Wilkie, Morven, Peter, Jonathan, Stockdale, Lisa, Manjaly-Thomas, Zita-Rose, Vermaak, Samantha, Satti, Iman, Moss, Paul, McShane, Helen
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2016
Materias:
Major Articles and Brief Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747614/
https://ncbi.nlm.nih.gov/pubmed/26450421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv482
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