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Flavokawain C Inhibits Cell Cycle and Promotes Apoptosis, Associated with Endoplasmic Reticulum Stress and Regulation of MAPKs and Akt Signaling Pathways in HCT 116 Human Colon Carcinoma Cells

Flavokawain C (FKC) is a naturally occurring chalcone which can be found in Kava (Piper methysticum Forst) root. The present study evaluated the effect of FKC on the growth of various human cancer cell lines and the underlying associated mechanisms. FKC showed higher cytotoxic activity against HCT 1...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Phang, Chung-Weng, Karsani, Saiful Anuar, Sethi, Gautam, Abd Malek, Sri Nurestri
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747580/
https://ncbi.nlm.nih.gov/pubmed/26859847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148775
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