Lipoicmethylenedioxyphenol Reduces Experimental Atherosclerosis through Activation of Nrf2 Signaling

OBJECTIVE: Oxidative stress is implicated in the pathogenesis of atherosclerosis, and Nrf2 is the transcriptional factor central in cellular antioxidant responses. In the present study, we investigate the effect of a dihydrolipoic acid derivative lipoicmethylenedioxyphenol (LMDP) on the progression...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ying, Zhekang, Chen, Minjie, Xie, Xiaoyun, Wang, Xiaoke, Kherada, Nisharahmed, Desikan, Rajagopal, Mihai, Georgeta, Burns, Patrick, Sun, Qinghua, Rajagopalan, Sanjay
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747573/
https://ncbi.nlm.nih.gov/pubmed/26859892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148305
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