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Hedgehog regulates angiogenesis of intersegmental vessels through the VEGF signaling pathway

The cellular mechanisms regulating branching and growth of the intersegmental vessels (ISVs) are not well understood. We have carried out studies demonstrating that Hedgehog (Hh) signaling is a major regulator of intersomitic vessel growth. Inhibition of Hh activity by cyclopamine completely blocks...

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Detalhes bibliográficos
Publicado no:Dev Dyn
Main Authors: Moran, Carlos M., Myers, Candace T., Lewis, Cristy M., Krieg, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747427/
https://ncbi.nlm.nih.gov/pubmed/22513894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.23795
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