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Hedgehog regulates angiogenesis of intersegmental vessels through the VEGF signaling pathway

The cellular mechanisms regulating branching and growth of the intersegmental vessels (ISVs) are not well understood. We have carried out studies demonstrating that Hedgehog (Hh) signaling is a major regulator of intersomitic vessel growth. Inhibition of Hh activity by cyclopamine completely blocks...

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Détails bibliographiques
Publié dans:Dev Dyn
Auteurs principaux: Moran, Carlos M., Myers, Candace T., Lewis, Cristy M., Krieg, Paul A.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747427/
https://ncbi.nlm.nih.gov/pubmed/22513894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.23795
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